The study of consciousness is poised today at interesting crossroads. There has been a surge of research into various neurobiological underpinnings of consciousness in the past decade. The present article looks at the theories regarding this complex phenomenon, especially the ones that neurobiology, cognitive neuroscience and cognitive psychology have to offer. We will first discuss the origin and etymology of word consciousness and its usage. Neurobiological correlates of consciousness are discussed with structures like the ascending reticular activating system, the amygdala, (...) the cerebellum, the thalamus, the frontoparietal circuits, the prefrontal cortex and the precuneus. The cellular and microlevel theories of consciousness and cerebral activity at the neuronal level contributing to consciousness are highlighted, along with the various theories posited in this area. The role of neuronal assemblies and circuits along with firing patterns and their ramifications for the understanding of consciousness are discussed. A section on the role of anaesthesia and its links to consciousness is presented, along with details of split-brain studies in consciousness and altered states of awareness, including the vegetative states. The article finally discusses the progress cognitive psychology has made in identifying and theorising various perspectives of consciousness, perceptual awareness and conscious processing. Both recent and past researches are highlighted. The importance and salient features of each theory are discussed along with the pitfalls, if present. A need for integration of various theories to understand consciousness from a holistic perspective is stressed, to enable one to reach a theory that explains the ultimate neurobiology of consciousness. (shrink)

The study of consciousness has today moved beyond neurobiology and cognitive models. In the past few years, there has been a surge of research into various newer areas. The present article looks at the non-neurobiological and non-cognitive theories regarding this complex phenomenon, especially ones that self-psychology, self-theory, artificial intelligence, quantum physics, visual cognitive science and philosophy have to offer. Self-psychology has proposed the need to understand the self and its development, and the ramifications of the self for morality and empathy, (...) which will help us understand consciousness better. There have been inroads made from the fields of computer science, machine technology and artificial intelligence, including robotics, into understanding the consciousness of these machines and their implications for human consciousness. These areas are explored. Visual cortex and emotional theories along with their implications are discussed. The phylogeny and evolution of the phenomenon of consciousness is also highlighted, with theories on the emergence of consciousness in fetal and neonatal life. Quantum physics and its insights into the mind, along with the implications of consciousness and physics and their interface are debated. The role of neurophilosophy to understand human consciousness, the functions of such a concept, embodiment, the dark side of consciousness, future research needs and limitations of a scientific theory of consciousness complete the review. The importance and salient features of each theory are discussed along with certain pitfalls, if present. A need for the integration of various theories to understand consciousness from a holistic perspective is stressed. (shrink)

Attention deficit hyperactivity disorder is a developmental disorder with an age onset prior to 7 years. Children with ADHD have significantly lower ability to focus and sustain attention and also score higher on impulsivity and hyperactivity. Stimulants, such as methylphenidate, have remained the mainstay of ADHD treatment for decades with evidence supporting their use. However, recent years have seen emergence of newer drugs and drug delivery systems, like osmotic release oral systems and transdermal patches, to mention a few. The use (...) of nonstimulant drugs like atomoxetine and various other drugs, such as a-agonists, and a few antidepressants, being used in an off-label manner, have added to the pharmacotherapy of ADHD. This review discusses current trends in drug therapy of ADHD and highlights the promise pharmacogenomics may hold in the future. (shrink)

This paper aims at taking a fresh look at Freudian psychoanalytical theory from a modern perspective. Freudian psychology is a science based on the unconscious and the conscious . Various aspects of Freudian thinking are examined from a modern perspective and the relevance of the psychoanalytical theory of consciousness is projected. Do psychoanalysis and the unconsciousness have something to teach us about consciousness? Approaching Freud from a historical, psychoanalytical, anthropological and sociological perspective, we need to look at how Freudian theory (...) may contribute to a better understanding of consciousness. We also need to look at psychoanalytical psychotherapy and its contribution to a better understanding of body-mind dualism and consciousness as a whole. Ego psychology is considered in the present day context and it is synthesized with various psychological studies to give us a better understanding of consciousness. (shrink)

The psychopharmacology of alcohol dependence is today poised at interesting crossroads. Three major drugs Naltrexone, Disulfiram and Acamprosate have been tried and tested in various trials and have many meta-analyses each to support them. While Naltrexone may reduce craving, Acamprosate scores on cost effectiveness worldwide with Disulfiram being an alcohol deterrent drug. Studies support, refute and criticize the use of each of these drugs. Combining one or more of them is also a trend seen. The most important factor in efficacy (...) has been the combination of psychosocial treatment with medication. Studies from the early 1970s to date have been reviewed and the findings presented in a manner useful for the busy clinician to judge the best pharmacological option in the management of alcohol dependence. The role of depot disulfiram, naltrexone, and medications like Topiramate and SSRIs under research for alcohol dependence, are also addressed. (shrink)